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They also carry a boxed warning about thyroid C-cell tumor risk and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

A randomised, double blind, placebo-crossover trial

Translationally, this perspective supports structured evaluation of micronutrient status aimed at maintaining enzymatic capacity rather than indiscriminate supplementation

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