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This information should be interpreted with a qualified healthcare provider and used to support a more personalized conversation about treatment candidacy and expected outcomes

Indeed, there are multiple primary or secondary bile acid chemosensors in the liver (348, 354) or scattered along the gastrointestinal tract (355), where they ensure a direct negative feedback aiding detoxification (356) and protecting from hepatotoxicity and carcinogenicity displayed by some secondary bile salt such as lithocholic acid

reported that in breast cancer cells, Erastin significantly increased the expression of key autophagy-associated proteins, including beclin-1, ATG5, ATG12, and LC3B, while concurrently decreasing levels of the autophagy substrate p62 (50)

This was a cell-system endpoint, not a clinical outcome

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