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In a clinical trial in pediatric patients aged 12 years and older for weight reduction, cholelithiasis was reported by 3.8% of WEGOVY-treated patients and 0% placebo-treated patients

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This activation, in turn, stimulates the transcription of HIF-1, thus forming a regulatory feedback loop [49]

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By listing device patents that do not even mention the active ingredient, innovators can trigger a 30-month stay on generic competition