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Description

M., Evelo, C

After three basal measurements, cells were permeabilized by injection of saponin (1 g/mL, Sigma S4521), together with 1 mM ADP (Sigma 01905) and the following respiratory complex substrates: CI, pyruvate/malate (5 mM/2.5 mM)

BarreaLAnnunziataGMuscogiuriGArnoneATenoreGCColaoAet al

This multi-receptor profile is why it is studied as a research tool for investigating combined incretin and glucagon-receptor signalling, in contrast to single- or dual-receptor peptides