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3 Tretinoin: A powerful retinoid, tretinoin has been shown to accelerate skin cell turnover, smooth fine lines, and promote collagen production

Head-to-Head: SURMOUNT-5 The first direct head-to-head trial (SURMOUNT-5, published 2024) compared tirzepatide and semaglutide specifically for weight loss

ENS neurotransmitters are also tied directly to the regulation of intestinal barrier functions, which control both the gut microbiota composition and immune responses

A clean off-cycle requires these to return to baseline before any subsequent cycle