GLP-1 receptors are found in several brain regions, including: The ventral tegmental area (VTA) The nucleus accumbens The prefrontal cortex When activated by GLP-1, these receptors appear to reduce the release of dopamine in response to addictive substances
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References: Sun Y, Veccia D, Liu BDX, Tse W, Fass R, Song G
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These dynamic processes involve the bone multicellular unit composed of osteoblasts, osteoclasts, and osteocytes within bone matrix ( via MAPK and Wnt signaling pathways to promote Runx2 activity (56)