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[] Free radicals damage the RBC products by lipid, protein oxidation and oxidative loss with changes in the structure of the RBCs membrane leads to an increase in the accumulation of band-3 protein, lipid oxidation and apoptotic changes in the last weeks of storage

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Reduced glutathione (GSH) and oxidized glutathione (GSSG) form an interconnected redox couple reflecting peroxide detoxification, thiol chemistry, and reducing capacity

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