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Whilst these studies seem to be making strides in breast cancer treatment, one other preclinical study saw obese mice (fed a high-fat diet) injected subcutaneously with pancreatic cancer cells and treated with Semaglutide or Retatrutide (another GLP-1R agonist)
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However, their benefits, such as L-citrullines role in muscle protein synthesis, are less pronounced than those of established nutrients like leucine, and claims of anti-tumor effects for either compound lack clinical validation, and require further research
As these drugs become more widely used for weight loss and metabolic conditions, clinicians and individuals alike are grappling with questions about how appetite-suppressing medications intersect with disordered eating patterns, body image concerns and recovery
