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Beyond current indications, Alberta Blue Cross identifies potential future expanded uses including: Metabolic dysfunction-associated steatohepatitis (MASH) [Source: ab.bluecross.ca/plans/group/drug-pipeline-2026.php] Obstructive sleep apnea (OSA) [Source: ab.bluecross.ca/plans/group/drug-pipeline-2026.php] The insurer characterizes the developing GLP-1 pipeline as robust, with treatments described as more effective, broader in use, and longer between doses [Source: ab.bluecross.ca/plans/group/drug-pipeline-2026.php]

Neuron 109 , 461472.e465 (2021)

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Ohkubo, Kei

241 In -cells of patients with T2DM, the ability of GLP-1(936) to inhibit glucagon secretion is lost