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Glucagon activation increases thermogenesis (heat production), enhances fat oxidation, and elevates metabolic rate

Thats where I see these drugs fitting in. For the foreseeable future, thats going to be a little bit of a difficult question to answer

Nutrition, exercise, sleep, and stress management all influence long-term weight loss success, even while taking medication

Inflammatory bowel disorders or gastroparesis: GLP-1 agonists slow gastric emptying and may worsen symptoms of inflammatory bowel disorders