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When mechanical forces are applied to the ACL, integrins transmit signals into the cell, leading to changes in gene expression and protein synthesis

Targeted molecular pathways involved include thyroid follicular cells, TSH receptors, and thyroid hormone receptors

Petersburg-based research team found that epitalon produced telomere elongation significant enough to allow cells to exceed the Hayflick limit, which describes the typical lifespan for a human cell

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