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Just make sure you're under medical supervision throughout your weight loss journey

Taking metformin has been known to increase constipation, bloating, belly cramps and diarrhoea in some patients

The abnormal proliferation of FLS results from a loss of contact inhibition that plays a critical role in RA by producing inflammatory cytokines and proteinases, such as matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) that perpetuate joint destruction

Dr Sethi calls it collagen banking, which is beginning treatments to stimulate collagen production before the weight loss happens, so that when fat does recede, the skin has the structural reserves to handle it

Yes, but only for patients who meet the relevant NICE criteria and can access an appropriate specialist weight-management pathway