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At 5 mg/mL, 100 units equals 5 mg, which is more than double the maximum approved weekly dose and would be considered an overdose

Contrary to other beneficial changes, HDL cholesterol has been reduced during semaglutide treatment

Doseresponse relationships for both agents were nonlinear, with greater incremental effects at lower doses and attenuation at higher doses, although the shape and extent of these relationships differed between drugs

This led to a global shortage of the medication as people flocked to get an Ozempic prescription