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Currently, the effects of 2.4 mg semaglutide once weekly are being explored in 1200 participants with biopsy-confirmed NASH in a Phase III clinical trial with a combined primary endpoint of resolution of NASH without worsening fibrosis, improvement in liver fibrosis without worsening of steatohepatitis, and time to first liver-related clinical event (NCT04822181) (see Table 2)

Furthermore, they noted that the mean inflammatory lesion count dropped from 5.1 at baseline to 2.8 (week 4) and 1.9 at week 8 for a total reduction of 63%

Common adverse effects include gastrointestinal symptoms such as nausea, diarrhea, and decreased appetite, which typically diminish over time as patients develop tolerance to the medication

Struggling to concentrate or noticing tingling in your hands and feet

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