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A central role of bile acid signaling as a novel pharmacological target in the metabolic syndrome and related diseases, such as obesity, T2D, atherosclerosis, liver disease, and cancer, is underscored by the presence of TGR5 in various tissues and cell types

It is available in a dosage strength of 500 mcg per actuation (0.1 mL/actuation)

Lingvay I, Mosenzon O, Brown K, Cui X, ONeill C, Fernndez Land L, et al

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Note that 100mg vials at daily 2mg dosing provide 50 days of product, which exceeds the 30-day reconstituted stability recommendation