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The starting dose is 0.25 mg once weekly for four weeks, followed by 0.5 mg for four weeks, then 1 mg for four weeks, then 1.7 mg for four weeks, and finally 2.4 mg once weekly as the maintenance dose

Amendments were documented in updated study protocols available on ClinicalTrials.gov

However, understanding potential indirect connectionssuch as nutritional changes from rapid weight loss or the elevated baseline RLS risk in diabetic populationshelps clinicians provide comprehensive patient care and appropriate symptom evaluation

[DOI] [PubMed] [Google Scholar] 101.Davies M., Frch L., Jeppesen O.K., Pakseresht A., Pedersen S.D., Perreault L., Rosenstock J., Shimomura I., Viljoen A., Wadden T.A., et al

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