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It's a less severe concern than, say, copper toxicity, but it's a practical safety issue that must be considered

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T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76

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Early significant results are sometimes limited to section analysis or have not been replicated, NAC has had inconsistent efficacy in treating a variety of psychiatric conditions

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10.1523/JNEUROSCI.2213-07.2007 178

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