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doi: 10.1093/ajcp/95.4.484 9 Prieto-RodrguezMCamaas-SanzABasTCortesBVera-SempereFJ

Despite several constraints, PHH rank among the most representative models for human hepatocytes

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The diagnosis of vitamin B12 deficiency typically relies on low total B12 levels and elevated concentrations of homocysteine (Hcy), as well as levels of transcobalamin-bound B12 (holoTC) and methylmalonic acid (MMA), which serve as functional indicators of cobalamin insufficiency (Carmel and Sarrai, 2006)

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