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Albert CM, Cook NR, Gaziano JM, Zaharris E, MacFadyen J, Danielson E, Buring JE, Manson JE

While direct cortisol measurements were not specifically reported in the published safety trials, the comprehensive metabolic monitoring across 900+ participants showed no clinically significant hormonal changes, and the mechanism of action provides no pathway for cortisol stimulation

Injections deliver glutathione directly into the bloodstream, which may provide faster and more noticeable results

(2022) 40:20118.e9

Funding The authors are grateful to the National Key Research and Development Program of China (2022YFD1300701, 2019YFE0115000) and the China Agriculture Research System of MOF and MARA (CARS-41)