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Klei TRL, Dalimot JJ, Beuger BM, Veldthuis M, Ichou FA, Verkuijlen P, et al

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Furthermore, a systematic review reported that erbium YAG lasers, fractional lasers, topical 5-FU, intramuscular injection of betamethasone, etc., improved the repigmentation effect as a combination therapy with narrow-band UVB55

Increasing levels of sodium (Na + ) and chloride (Cl ) ions, lead to ionic imbalance by accumulating in tissues, hindering mineral nutrient uptake