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Hormonal balance, topical interventions, and stress modulation are powerful levers in slowing visible and biological aging

The weight loss is clinically important, as most individuals with type 2 diabetes are overweight or obese, but also because there is an unmet need for safe, effective, and durable weight loss interventions in obese individuals without diabetes

Once activated, these receptorligand complexes regulate gene transcription through vitamin D response elements (VDREs), affecting pathways involved in keratinocyte proliferation, differentiation, and inflammation (Pike et al