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For example, in head-to-head trials, patients on the highest dose of Zepbound lost up to 22.5% of their body weight over 72 weeks, while those taking semaglutide GLP-1 (Wegovy) lost about 15% over a similar period

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doi: 10.1016/j.cgh.2018.12.031 [DOI] [PMC free article] [PubMed] [Google Scholar] 20.Xiao G, Zhu S, Xiao X, Yan L, Yang J, Wu G

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No benefit in terms of the risk of HF hospitalization was observed with oral semaglutide, as well as with efpeglenatide (43, 44)

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