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Cytotoxicity of the novel glutathione-activated thiopurine prodrugs cis -AVTP [ cis -6-(2-acetylvinylthio)purine] and trans-AVTG [trans-6-(2-acetylvinylthio)guanine] results from the National Cancer Institutes anticancer drug screen

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This effect of isoniazid was subsequently found to be the result of its inhibition of MAO