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HIF activation reprograms cellular metabolism by upregulating glycolytic gene expression in inhibiting pyruvate entry into the TCA cycle [53], thereby mediating a shift from oxidative phosphorylation to glycolysis

Sometimes deficiencies can also occur due to genetic factors or lifestyle choices, such as smoking or specific medication use, like antibiotics

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Custom cerium oxide nanoparticles protect against a free radical mediated autoimmune degenerative disease in the brain

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