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The warnings and precautions section covers acute pancreatitis, diabetic retinopathy complications, acute gallbladder disease, acute kidney injury from volume depletion, severe gastrointestinal reactions, hypersensitivity reactions, hypoglycemia when used with insulin or an insulin secretagogue, and pulmonary aspiration during general anesthesia or deep sedation

PMC 6543499

[55] established a rat kidney stone model by injecting glyoxalate and found that the mitochondria in rat RTECs became smaller and increased in membrane density, and the mitochondria were severely damaged

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This both improves absorption and stimulates lymphatic drainage