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A 2016 phase 1B clinical trial, investigating the efficacy of NSI-189 in a randomized, placebo-controlled study design, indicated significant effects of the drug as orally administered to individuals suffering from MDD either once, twice or three times per day

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They do not interfere with each other and may work in a complementary way to support gut health and immune function

This cpFP has been adapted in designing ATP indicator, ATeam 13 and NADPH sensor (iNAP) 14

1 Introduction In recent years, with the popularity of electronic devices such as computers and smartphones, people are increasingly exposed to artificial light sources (Ouyang et al., 2020), and prolonged exposure to light has become a major challenge affecting public visual health