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This cytokine induces its own expression in activated HSCs, thereby creating a self-perpetuating cycle of events, referred to as an autocrine loop

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

While treatment with rhGH in normal mice increases body weight, lean body mass, and liver weight but does not increase hepatic expression and release of IGF1, suggesting IGF1 is not a reliable indicator of the biological effects of exogenous GH treatment in genetically and pharmacologically unmodified individuals (Yamauchi and Pessin, 1994