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Intermittent short-duration reoxygenation relieves high-altitude pulmonary hypertension via NOX4/H2O2/PPAR-gamma axis

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Dumbrava EI, Call SG, Huang HJ, Stuckett AL, Madwani K, Adat A, Hong DS, Piha-Paul SA, Subbiah V, Karp DD, Fu S, Naing A, Tsimberidou AM, Moulder SL, Koenig KH, Barcenas CH, Kee BK, Fogelman DR, Kopetz ES , Meric-Bernstam F, Janku F

Probiotic intervention can counteract such disruptive fluctuations: In a study of DSS-induced colitis, administration of Lactobacillus rhamnosus GG (LGG, 10 9 CFU/day) markedly improved microbiota diversity, reversing dysbiosis by enriching beneficial taxa such as Bifidobacterium, Olsenella, Paenibacillus , and butyrate-producing bacteria (33)