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The Mayo Clinic cohort: women on semaglutide plus HRT lost more weight at every timepoint (and it wasnt explained by confounders)

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Hematology and biochemistry laboratory parameters were measured at screening and weeks 20, 52, 84 and 104

And people need to exercise and do resistance training so they can be sure to maintain muscle mass

Since Semaglutide is diabetes medication, the mechanism of action of semaglutide involves increasing sensitivity to insulin, which helps reduce overall circulating glucose and ultimately lowers the average blood sugar level