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That said, the AACE consensus statement (2025) already suggests that tirzepatide could replicate semaglutides kidney benefits, lending support to the view that CKD impact may reflect a class effect, rather than a single-agent effect

however, they are significantly enriched in the pancreas of AAb+ and T1D patients with no differences between pancreatic compartments ( in vitro transwell-based extravasation assays

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Contribution of relapse-independent progression vs relapse-associated worsening to overall confirmed disability accumulation in typical relapsing multiple sclerosis in a pooled analysis of 2 randomized clinical trials