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While the PiP-MS technique does not provide direct insight into cellular status due to its application to cell lysates, it enables the investigation of how cellular growth conditions and proteasome variants impact the 20S substratome

The presence of the biofilm phenotype contributes to diagnostic and treatment challenges, including considerably increased antibiotic tolerance and treatment failure leading to additional surgeries, amputation, and death is not uncommon (3)

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We are using both these medications with our patients with really good results, and we are happy to set up an initial evaluation

Oral or intravenous antibiotics