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We did not receive specific comments on our proposed calculation of the scaling factor, so we are finalizing that calculation as proposed at 512.750(c)(1)(iv)

Setting expectations appropriately based on individual circumstances helps maintain adherence through the time needed for full benefit

Other people who are at risk of having vitamin B12 deficiency include those who have had intestinal surgery, or who have gut diseases like Crohns disease or celiac disease

In a clinical or home setting (with proper guidance), it is often injected in areas such as the upper arm, thigh, hip, or buttock

Rarely, individuals may notice temporary dizziness or a flushed feeling