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This research was supported by funding from Diabetes UK (18/0005884 to JR, RD Lawrence Fellowship 21/0006280 to GM), the Biotechnology and Biological Sciences Research Council (BB/V015869/1 to JJR, BB/R01857X/1 and BB/V016849/1 to LH), the Wellcome Trust Institutional Strategic Support Fund to the University of Aberdeen (to LH and JR)

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