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these reverse on discontinuation) Fasting glucose or HbA1c in T2D patients: every four weeks during taper, then at 3 months and 6 months post-discontinuation Lipid panel: at baseline taper start and at 3 months post-discontinuation (GLP-1s reduce LDL by approximately 3 to 5% and triglycerides by 10 to 20% on average
(2020) 105:e25632571
The sustained action of glucagon causes hyperglycemia and glucose mediated inhibition of glucagon secretion is impaired in patients with T2DM
Here is what a typical 6-week drug holiday timeline looks like based on pharmacokinetic data and clinical reports
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