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Clinical evidence supports these anti-inflammatory effects

When it binds these ligands outside the cell, it lowers their ability to activate receptors such as ActRIIA and ActRIIB, which can shift SMAD2/3 signaling and gene expression

Inflammation (2020) 43:172941

M., & Wathoni, N

Oocytes treated with 0.1 mM Epitalon showed significantly improved MMP compared to untreated aged oocytes, demonstrating that Epitalon preserves mitochondrial function during in vitro aging