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Ethics declarations Ethics approval and consent to participate All animal experiments followed the ARRIVE guidelines and adhered to the U.K

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We have challenged ourselves to make products that are denser in nutrients than calories, so every single mouthful is packed full of more of the nutrients we all need. As GLP-1 users have suppressed appetites, M&S has focused on recipes that contain a very high amount of nutrients per calorie

The gut-brain axis has emerged as a compelling therapeutic target, yet existing monotherapies exhibit inherent mechanistic incompleteness

Hypertension has been observed to be a side effect directly correlated with oxidative stress, thus supporting the argument that the overexpression of ACE2 leads to a lowering of oxidative stress in a biological system [14]