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Furthermore, certain variants of the ACE gene, such as the D allele, are more frequently noted in patients with affective disorders and associated with a higher risk of affective disorders (63)

There is one exception: if Wegovy is prescribed for a covered indication other than weight loss (the drug has a separate FDA approval for cardiovascular risk reduction in adults with established cardiovascular disease and BMI 27), some Medicare plans may cover it under that indication

Long-term use should always be supervised by a clinician familiar with peptide therapy

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