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For tesamorelin, known adverse effects (based on US and Canadian prescribing information, as no UK Summary of Product Characteristics exists) include: Fluid retention (oedema, joint pain, carpal tunnel syndrome) Elevated blood glucose and reduced insulin sensitivity due to GH elevation Injection site reactions Raised IGF-1 levels active malignancy is a key contraindication

V.SpoonerL.VostersJ.DominguezS.PatrickL.HarrisA.et al (2024)

It may support nitric oxide, circulation and blood flow

Its ability to cross the blood-brain barrier means it plays an important role in removing toxins, such as mercury, from the brain and other cells

Oral Wegovy Dosage: How to Take Your Medication When beginning treatment, your provider will likely start with a lower dose, gradually increasing it to minimize any side effects