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Your provider may recommend: Shorter time at the 2.5 mg initiation dose (3 weeks instead of 4) More aggressive titration to reach therapeutic levels sooner Targeting higher maintenance doses (12.5 to 15 mg) from the outset Closer monitoring of side effects to balance speed with tolerance The microdosing alternative for sensitive switchers Not everyone needs or wants to follow the standard titration

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This is usually not enough to cause significant degradation over the life of a single vial, but combined with other stress factors, it contributes

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Several 2026 developments are reshaping how providers and patients approach treatment: TMS FDA-cleared for OCD: Transcranial Magnetic Stimulation (TMS) targeting the anterior cingulate cortex is now FDA-cleared for OCD