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The primary mechanism of Semax involves significant upregulation of BDNF and nerve growth factor, which promote neuroplasticity and neuronal survival

Damage to mitochondrial biogenesis resulting from defective mitophagy may result in a decrease or increase in the number of mitochondria (Palikaras et al., 2015)

Enhanced with the substitution of an Arginine for the third position of its amino acid sequence and an extension peptide at the N-terminus, IGF-1 LR3 is designed to boost the biological activity of the IGF hormone

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