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Upon cell internalization via endocytosis mechanisms, these nanoparticles disrupt endosomal membranes through the proton sponge effect, facilitating the intracellular delivery of exogenous nucleic acids

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Combining phentermine with tirzepatide can increase the risk of dehydration through additive appetite suppression

Our findings revealed that Y1-R signaling directly stimulated glucose uptake in muscle tissue via a pathway that is independent of insulin-stimulation

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