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The amount of copper in topical GHK-Cu products is far too small to cause systemic copper toxicity

Monitor for localized metabolic dullness, nausea, or altered gastric emptying, which are common secondary responses during the maintenance phase

Pharmacodynamics: KPV is a melanocortin-derived tripeptide that regulates immune activity by inhibiting NF-B signaling and reducing the expression of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6

It could be a sign of contamination or that the peptide has been damaged

Now perhaps most importantly for this talk is this experiment, which was done in collaboration with Bruce Ksander and Meredith Ksander at Gregorys Lab, and what we took what we did, you maybe familiar, is you can increase intraocular pressure, IOP, for a month in a mouse by putting these microbeads in this region of the iris, next to the iris