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For diabetic patients, this poses a substantial threat, as corticosteroids are known to induce hyperglycemia [34]

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The increase in Ca 2+ is mediated by IP3 induced release of intracellular Ca 2+ and by depolarization leading to activation of voltage dependent Ca 2+ channels

We found that GE2 treatment significantly increased plasma GLP-1 compared to vehicle in females ( p = 0.001

Notably, the American Diabetes Association advocates for the utilization of GLP-1 RAs with established cardiovascular benefits in patients diagnosed with type 2 diabetes and concurrent cardiovascular disease