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By striving to reconcile the disparity between its considerable neuroprotective potential and recent clinical challenges, we can enhance our understanding of the potential role of semaglutide and other GLP-1 receptor agonists in combating cognitive decline

Although patients with severe conditions were excluded, the absence of multivariate analysis limited adjustment for confounders

It describes most reported headaches as mild to moderate and rarely severe enough to stop treatment

The ideal spacing for a twice-weekly protocol is 72-84 hours

Dolores Keating, Pharmacy Department, Saint John of God Hospital, Dublin, A94 FH92, Ireland