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Less commonly recognized but still valid qualifying conditions include prediabetes (elevated fasting glucose or A1C between 5.7-6.4%), polycystic ovary syndrome, non-alcoholic fatty liver disease, osteoarthritis of weight-bearing joints, and chronic kidney disease

doi: 10.1136/gutjnl-2022-327909 157 XueYLuFChangZLiJGaoYZhouJet al

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In the conclusion, these associations can highlight the possibility that changes of antioxdiants have a significant role on neurodegenerative diseases

4.5 Ferrostatin-1 Fer-1 acts as a lipophilic free radical scavenger due to its redox cycling activity (Doll and Conrad 2017), and alleviates ferroptosis by inhibiting lipid peroxidation and preventing GPX4 deletion or GSH depletion (Zilka et al., 2017