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A: Clinical studies confirm that liposomal delivery drastically increases cellular absorption

PMID: 191 StephanKEManjalyZMMathysCDWeberLAPaliwalSGardTet al

The 13-amino-acid N-terminal extension (sequence MFPAMPLLSLFVN) shifts the three-dimensional conformation of the binding interface, while the Arg 3 Glu 3 substitution disrupts a key contact residue with IGFBPs