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The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance

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PLoS One 7:e49524 Vendemiale G, Grattagliano I, Altomare E, Turturro N, Guerrieri F (1996) Effect of acetaminophen administration on hepatic glutathione compartmentation and mitochondrial energy metabolism in the rat

424 Moreover, the two components of the G3P shuttle (including GPD1 in the cytoplasm and GPD2 in the mitochondria) are up-regulated in mRNA and protein levels in diabetic islets, thus ensuring the transfer of electrons from NADH produced in glycolysis to mitochondria