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Most likely, the main risk is reduced effectiveness rather than immediate harm

In clinical studies, liraglutide and semaglutide both led to an average 0.3-point drop in A1c in prediabetic participants (after 56 weeks for liraglutide 5 and 68 weeks for semaglutide 6 )a small but meaningful shift for people whose blood sugar is creeping upward toward the diabetes threshold

Uh, the other thing is that I think we just need to say that, you know, these are not for everyone

These effects typically resolve within one to two weeks of adjusting to the new dose, following the same adaptation pattern you experienced initially