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Within the cell, approximately 90% of glutathione is located in the cytosol, 10% in the mitochondria and a small percentage in the endoplasmic reticulum [29]

These could provide insights on why some variants may cause a higher degree of phenotypic severity compared to others

The articles were collected, organized, and sorted using the Covidence software (Melbourne, Australia) for systematic review

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Research has explored its activity in glucose metabolism, insulin signaling pathways, and mitochondrial function in controlled laboratory environments