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The rationale, indications, contraindications, and general approach to this procedure are covered in the first article in this series

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L-NAME rats exhibited the moderate generalized irregularity in the diameter of blood vessels with moderate atrophy of the optic disc, faint presentation of the choroidal blood vessels appearing immediately, and these lesions (Figure 2, IN, IIN), and a rapid progress to the severe stage (Figure 3, AC